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Clinicogenomics for greater data insights

Better understand diseases and drug development opportunities with our genomics solution.

Unlock the potential of genomic data

The information within the human genome can help us diagnose rare diseases, identify individuals at risk of developing certain conditions and create effective treatment regimens. But today’s genomic data sets often come with limitations for researchers. They’re noisy, not representative, and lack information on the patient journey, limiting their value.

Optum Life Sciences combines the rich depth of genomic sequencing data with our world-class clinical and claims assets to offer researchers a new frontier in their search for life-changing treatments, vaccines and cures. Our research-ready, de-identified clinicogenomics data sets link genomic and other -omic data with the longitudinal health record, allowing for:

  • Genotypic and phenotypic research across all stages of therapy development and use in the real world
  • Comparison of clinical trial data to real-world data (RWD)
  • Development of companion diagnostics
  • Understanding the genetic testing landscape

With these real-world data, your teams can spend less time on unproductive research and development, and accelerate the time to market for innovative, targeted therapies.

Designed with the real world in mind

Clinicogenomics data sets should reflect real-life populations. Ours are built to be representative and depict real clinical care.


High-quality RWD foundation

More than 115 million lives of de-identified clinical data allow for more detailed patient journeys from the start.


Data for all therapeutic areas

Beyond our 117,000 individual oncology patients linked with genomic data, our data spans thousands of conditions, including rare diseases.


Real-world populations reflected

For some therapeutic areas, you can design cohorts that are 100% non-Caucasian to analyze specific demographic trends.


Full patient journeys uncovered

Because tumor biology changes over time, our oncology data include sequential sequencing for over 15% of individuals.


Raw sequencing files

Our genomic data comes from raw sequencing files, rather than PDFs or other EMR-based reports.


Research across product lifecycles

From biomarker discovery, to market access, to creating external control arms, our diversified data sets help answer a variety of questions.

How clinicogenomics data can catalyze research

Our white paper shares how this cutting-edge resource can fuel all stages of development.

Research-ready, on-demand data sets

Explore longitudinal phenotypic data that are linked to genomic data and designed to help you answer specific research questions. Download our fact sheets for these therapeutic areas.

Cardiology and metabolic conditions

Optum can focus a customized cohort on individuals who are diverse with unique combinations of comorbid profiles.


Enable precision medicine, reveal the patient journey both before and after diagnosis, and help uncover new information about cancer types.

Autoimmune and inflammatory conditions

Explore the clinical and genomic pillars that reveal which patient populations should receive targeted treatments.

Fuel your next discovery

Streamline drug research and development process through discovery of high-value biomarkers, the genetic landscape and barriers to access.

Are You Maximizing the ROI of Your Real-World Data?

Help your organization capitalize on these vital resources using lessons and tools compiled by the Optum life sciences real-world data team.

Challenges and opportunities with clinicogenomic data

Genomic data linked to the longitudinal health record hold great insight. How should researchers think about and use these powerful data?

Clinicogenomics: new, linked data is advancing research

Rich, longitudinal clinicogenomics data can fuel all stages of drug development.

Complementary solutions

Strengthen your value story with HEOR

Tap into our expertise in health economics and outcomes research (HEOR).

Engage payers with value-based contracts

Assess the fit, develop metrics and track care outcomes over time.

Generate evidence with real-world data

Derive evidence from the unmatched depth and scale of our data assets.