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Recruit more patients and reduce trial burden

The Optum® Digital Research Network processes streaming electronic health record (EHR) data and notes from health systems. 

By leveraging natural language processing (NLP) to get information that is typically difficult or impossible to access in a structured way, you can access key services today.


Reduce trial disruption and help define the next generation of clinical research

  • Collaborate with pharmaceutical and device sponsors on post-market studies that leverage real-world data 
    • Clinical trials designed using data to fit with normal course of care
    • Clinical trials designed to collect data on outcomes and adverse events directly from structured and unstructured EHR data
  • Use the near real-time EHR as a streaming source for clinical trial data collection
    • Data processed, curated and archived directly from the EHR (no case report forms (CRFs), no electronic data capture (EDCs))

Push the boundaries of clinical research

  • Query structured and unstructured data to estimate eligible patient population.
    • Site-specific patient counts
    • Rolling patient eligibility forecasts
    • Patient-physician attribution
  • Compare current standard of care to trial protocol requirements.
  • Maintain up-to-date registry of eligible patients based on trial inclusion/exclusion criteria.
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How it works

see below for full text

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  • Infographic showing a cycle of steps: 

    1. Right sites for the trial using data
    2. Optum collects and transfers data for those patients to the sponsor in accordance with clinical research regulations
    3. Site decides to participate in the trial and recruits patients (facilitated by data and tools to assess feasibility and create a patient registry), example: 100 patients identified as potentially eligible, 10 are consented and enrolled
    4. Optum and the sponsor design a trial using real-world data

    Cycle repeats with step 1.


Increase patient access to cutting-edge therapies and improve clinical research efficiency.


Trial protocol, inclusion/exclusion criteria


Optum analytics structured and unstructured data


Trial feasibility, eligible patient population estimates and forecasts, patient registry


Benefits to provider site

  • Trials are well suited to organization, patient recruitment/enrollment is higher
  • Manual data collection processes are eliminated/reduced
  • Real-world data allows for research insights to rapidly feed back into care processes